Omophub MCP Server

Search, lookup, map, and navigate OMOP medical vocabularies via AI agents

Remote serverstreamable-httpPython

What is the Omophub MCP server?

Most developer tooling work still happens through a UI a human drives. Omophub MCP server moves it into the conversation instead. Search, lookup, map, and navigate OMOP medical vocabularies via AI agents.

The short version

Search, map, and navigate 10M+ OMOP concepts: SNOMED CT, ICD-10, RxNorm, LOINC, and more. Directly from Claude, Cursor, VS Code, or any MCP-compatible client.

  • Concept lookup — - Find OMOP concept IDs for clinical terms in seconds
  • Cross-vocabulary mapping — - Map between ICD-10, SNOMED, RxNorm, LOINC, and 100+ vocabularies
  • Hierarchy navigation — - Explore ancestors and descendants for phenotype definitions
  • Concept set building — - Let your AI agent assemble complete concept sets for cohort definitions
  • Code validation — - Verify medical codes and check their standard mappings

The tools it exposes

The server publishes 13 tools. What each one is for:

  • search_concepts — Search for medical concepts by name or clinical term across all vocabularies
  • get_concept — Get detailed info about a specific OMOP concept by concept_id
  • get_concept_by_code — Look up a concept using a vocabulary-specific code (e.g., ICD-10 E11.9)
  • map_concept — Map a concept to equivalent concepts in other vocabularies
  • get_hierarchy — Navigate concept hierarchy - ancestors, descendants, or both
  • list_vocabularies — List available medical vocabularies with statistics
  • semantic_search — Search using natural language with neural embeddings (understands clinical meaning)
  • find_similar_concepts — Find concepts similar to a reference concept, name, or description
  • explore_concept — Get concept details, hierarchy, and cross-vocabulary mappings in one call
  • fhir_resolve — Resolve a FHIR coded value (incl. administrative codes via the HL7 FHIR-to-OMOP IG ConceptMaps) to its OMOP standard concept and CDM target table
  • fhir_resolve_codeable_concept — Resolve a FHIR CodeableConcept — best match by OHDSI vocabulary preference, honoring userSelected
  • Resources — The Resources tool exposed by this server

Getting it running

Because this one is hosted, setup is mostly authentication — you point your client at the endpoint and approve access. Nothing runs on your machine, so there is no runtime to keep patched.

What it needs from you

Configuration is passed through the environment: OMOPHUB_API_KEY, OMOPHUB_BASE_URL. Treat anything key-shaped as a real credential — scope it to the minimum the server needs, and rotate it if it ever lands in a shared config.

How it compares

Among the developer tooling options, the useful question is rarely "what can it do" but "what does it cost you to run" — permissions, credentials, and how much of your context its toolset consumes. Omophub's toolset — search_concepts, get_concept, get_concept_by_code and 10 more — is a fair guide to whether it matches your workflow. It is maintained by OMOPHub; worth a glance at recent repository activity before you build anything load-bearing on it.

This entry was verified against Omophub's own documentation before publication; SyncDev keeps the directory reviewed rather than auto-generated.

Things to watch

  • Your data travels to the provider's service, so the usual questions apply about what you send and what they retain.
  • With 13 tools registered it takes up a noticeable share of the context window; turn it off in projects that never touch Omophub.
  • Missing credentials fail quietly in some clients — if no tools show up, check the environment block first.
  • Keep per-call confirmation enabled while you learn its behaviour; it is the cheapest safeguard you have.

Available tools

ToolWhat it does
search_conceptsSearch for medical concepts by name or clinical term across all vocabularies
get_conceptGet detailed info about a specific OMOP concept by concept_id
get_concept_by_codeLook up a concept using a vocabulary-specific code (e.g., ICD-10 E11.9)
map_conceptMap a concept to equivalent concepts in other vocabularies
get_hierarchyNavigate concept hierarchy - ancestors, descendants, or both
list_vocabulariesList available medical vocabularies with statistics
semantic_searchSearch using natural language with neural embeddings (understands clinical meaning)
find_similar_conceptsFind concepts similar to a reference concept, name, or description
explore_conceptGet concept details, hierarchy, and cross-vocabulary mappings in one call
fhir_resolveResolve a FHIR coded value (incl. administrative codes via the HL7 FHIR-to-OMOP IG ConceptMaps) to its OMOP standard concept and CDM target table
fhir_resolve_codeable_conceptResolve a FHIR CodeableConcept — best match by OHDSI vocabulary preference, honoring userSelected
ResourcesThe Resources tool exposed by this server.
PromptsThe Prompts tool exposed by this server.

How to install the Omophub MCP server

{
  "mcpServers": {
    "omophub": {
      "command": "npx",
      "args": ["-y", "@omophub/omophub-mcp"],
      "env": {
        "OMOPHUB_API_KEY": "oh_your_key_here"
      }
    }
  }
}

Configuration as documented by the project. Restart the client after saving.

Configuration

VariableDescriptionRequired
OMOPHUB_API_KEYCredential the server authenticates with.Yes
OMOPHUB_BASE_URLEndpoint or connection string the server talks to.Yes

Example prompts to try

  • Use Omophub to search concepts.
  • Use Omophub to get concept.
  • Use Omophub to get concept by code.

Frequently asked questions

It connects Omophub to MCP-compatible AI assistants such as Claude and Cursor, exposing 13 tools (search_concepts, get_concept, get_concept_by_code, and more) that the assistant can call on your behalf. Instead of copying data back and forth by hand, the assistant works with Omophub directly.