How do I install the uniprot mcp server?

Use a recorded configuration for your client, replace example credential values and paths, and verify the documented runtime. Restart or reconnect the client, then inspect the available tools.

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Uniprot MCP Server

A Model Context Protocol (MCP) server that provides access to UniProt protein information. This server allows AI assistants to fetch protein function

Local serverstdioPython

What is the Uniprot MCP Server?

Uniprot mcp server lets Claude, Cursor and other MCP clients work with Uniprot directly. A Model Context Protocol (MCP) server that provides access to UniProt protein information. This server allows AI assistants to fetch protein function and sequence information directly from UniProt.

What Uniprot does

A Model Context Protocol (MCP) server that provides access to UniProt protein information. This server allows AI assistants to fetch protein function and sequence information directly from UniProt.

Key capabilities

Get protein information by UniProt accession number
Batch retrieval of multiple proteins
Caching for improved performance (24-hour TTL)
Error handling and logging
Information includes:
Function description
Full sequence
Sequence length

Practical notes

Maintained by TakumiY235, written in Python.

More MCP options

Compare MCP servers by category, or browse hosted MCP servers if you prefer an endpoint over a local process.

Maintainer setup documentation.

How to install the Uniprot MCP Server

{
  "mcpServers": {
    "uniprot": {
      "command": "uv",
      "args": [
        "--directory",
        "path/to/uniprot-mcp-server",
        "run",
        "uniprot-mcp-server"
      ]
    }
  }
}

From the project documentation. Replace placeholders and example paths before connecting.

Example prompts to try

“Use Uniprot to Tools.”

Frequently asked questions

A Model Context Protocol (MCP) server that provides access to UniProt protein information. This server allows AI assistants to fetch protein function and sequence Confirm the tools offered by your installed version in the connected client. Tool availability and permissions depend on the server and account configuration.