OpenTargets MCP Server

Opentargets mcp server connects OpenTargets to AI assistants that speak the Model Context Protocol. Production-ready MCP server for Open Targets gene-drug-disease associations.

What OpenTargets does

Unofficial Model Context Protocol server for accessing Open Targets platform data for gene-drug-disease associations research.

Tools it exposes

Once connected, the assistant can call these 3 tools directly:

• Version — Open Targets v25.0.1
• Authentication — None required
• Format — GraphQL queries, JSON responses

Installing the opentargets mcp server

The server is distributed via npm as npm, so most clients can run it without a manual build step. Add it to your MCP client's configuration and restart the client to pick it up — the copy-paste configs for Claude Desktop, Claude Code and Cursor are on this page.

Where it fits

Developer-tool servers are usually the first ones people connect, because they turn "help me with this code" into an assistant that can actually read the repo and act on it. OpenTargets sits in that group, and the shape of its toolset — Version, Authentication, Format — tells you what it is really for. Worth comparing against the other developer tools servers in this directory before you commit to one, since several overlap in scope but differ sharply in setup cost and permissions.

Practical notes

• This server runs locally, so it operates with whatever access your machine and its credentials already have. Scope that deliberately rather than by default.
• Maintained by Augmented-Nature, written in TypeScript.
• MCP clients ask for confirmation before each tool call by default. Keep that on while you learn what the opentargets mcp server actually does with your data.
• Every entry in this directory is reviewed by hand before it goes live, and details are checked against the project's own documentation.