Open Targets Official Remote MCP Server

Open targets official remote mcp server lets Claude, Cursor and other MCP clients work with Open Targets Official Remote directly. Drug target discovery data.

What Open Targets Official Remote does

This package is the official Open Targets Platform MCP server implementation that enables AI assistants to interact with the Open Targets Platform GraphQL API, a comprehensive resource for target-disease associations and drug discovery data.

Key capabilities

• 🔍 Category-Based Schema Access: Fetch and explore focused subsets of the Open Targets Platform GraphQL schema using category-based subschemas
• 🚀 Pre-fetched Schema Optimization: The GraphQL schema is pre-fetched and cached at server startup to ensure immediate availability for tools
• 📊 Query Execution: Execute custom GraphQL queries against the Open Targets Platform API
• ⚡ Batch Query Processing: Execute the same query multiple times with different parameters efficiently
• 🔎 Entity Search: Search for entities across multiple types (targets, diseases, drugs, variants, studies)
• 🛠️ CLI Tools: Easy-to-use command-line interface for starting the server
• 🎯 jq Filtering (Optional): Server-side JSON processing using jq to reduce token consumption and improve performance. See jq Filtering for details

Tools it exposes

Once connected, the assistant can call these 2 tools directly:

• otp-mcp — Shorter alias (recommended)
• open-targets-platform-mcp — Full command name

Installing the open targets official remote mcp server

Setup follows the standard MCP pattern: clone or install the server, then register it in your client's configuration file and restart the client. The configuration snippets on this page cover Claude Desktop, Claude Code and Cursor.

Configuration

The server reads 3 environment variables: OTP_MCP_TRANSPORT, OTP_MCP_JQ_ENABLED, OTP_MCP_HTTP_HOST. Keep credentials in your client's env block or a secrets manager rather than committing them.

Where it fits

Developer-tool servers are usually the first ones people connect, because they turn "help me with this code" into an assistant that can actually read the repo and act on it. Open Targets Official Remote sits in that group, and the shape of its toolset — otp-mcp, open-targets-platform-mcp — tells you what it is really for. Worth comparing against the other developer tools servers in this directory before you commit to one, since several overlap in scope but differ sharply in setup cost and permissions.

Practical notes

• This is a hosted server — you point your client at an endpoint rather than running a local process, so there is nothing to keep updated on your machine.
• Written in Python.
• MCP clients ask for confirmation before each tool call by default. Keep that on while you learn what the open targets official remote mcp server actually does with your data.
• Every entry in this directory is reviewed by hand before it goes live, and details are checked against the project's own documentation.