ENCODE Toolkit MCP Server

20 MCP tools + 48 skills for ENCODE Project genomics — search, download, pipelines

Local serverstdioGo

What is the ENCODE Toolkit MCP Server?

20 MCP tools + 48 skills for ENCODE Project genomics — search, download, pipelines

What you get

Search ENCODE, cross-reference 14 databases, run 7 analysis pipelines, and generate publication-ready methods — all from natural language in Claude Code.

More MCP options

Compare MCP servers by category, or browse hosted MCP servers if you prefer an endpoint over a local process.

Maintainer setup documentation.

Recorded tools

Check the linked publisher documentation and your connected client's tool list. Names and availability can vary with the server version and account permissions.

ToolWhat it does
encode_search_experiments
encode_get_experimentGet full details for a single experiment including all files, quality metrics, and audit info.
encode_download_files
encode_batch_downloadSearch + download in one step. Runs in preview mode by default.
encode_track_experimentTrack an experiment locally with its publications, methods, and pipeline info.
encode_list_filesList files for a specific experiment with format/type filters.
encode_search_filesSearch files across all experiments with combined experiment + file filters.
encode_get_metadata
encode_get_facetsGet live counts from ENCODE showing what data exists for given filters.
encode_get_file_info
encode_manage_credentialsStore, check, or clear ENCODE credentials for restricted data access.
encode_list_trackedList all experiments in your local tracker with metadata, publication counts, and derived file counts.
encode_get_citationsGet publications for tracked experiments. Export as BibTeX or RIS for reference managers.

How to install the ENCODE Toolkit MCP Server

{
  "mcpServers": {
    "encode-toolkit": {
      "command": "npx",
      "args": ["-y", "encode-toolkit"]
    }
  }
}

Add to claude_desktop_config.json, then restart Claude Desktop.

Example prompts to try

  • “Use ENCODE Toolkit to BibTeX.”
  • “Use ENCODE Toolkit to encode search experiments.”
  • “Use ENCODE Toolkit to encode get experiment.”

Frequently asked questions

20 MCP tools + 48 skills for ENCODE Project genomics — search, download, pipelines Confirm the tools offered by your installed version in the connected client. Tool availability and permissions depend on the server and account configuration.