How do I install the clinicaltrialsgov mcp server?

Use a recorded configuration for your client, replace example credential values and paths, and verify the documented runtime. Restart or reconnect the client, then inspect the available tools.

What credentials does it need?

It reads `MCP_TRANSPORT_TYPE`, `CT_API_BASE_URL` from the environment. Store these in your client's env block or a secrets manager — never commit them to a repository — and grant the narrowest scope that still covers your use case.

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Clinicaltrialsgov MCP Server

Search ClinicalTrials.gov trials, retrieve study details and results, and match patients to eligible trials via MCP. STDIO or Streamable HTTP.

Remote serverstreamable-http

What is the Clinicaltrialsgov MCP Server?

Search ClinicalTrials.gov trials, retrieve study details and results, and match patients to eligible trials via MCP. STDIO or Streamable HTTP.

What the server does

Seven tools for searching, discovering, analyzing, and matching clinical trials:

Declarative tool/resource/prompt definitions with Zod schemas and format functions
Unified error handling — handlers throw, framework catches and classifies
Dual transport: stdio and Streamable HTTP from the same codebase
Pluggable auth (none, jwt, oauth) for HTTP transport
Structured logging with optional OpenTelemetry tracing
Type-safe client for the ClinicalTrials.gov REST API v2

Credentials and setup notes

Bun v1.3.0 or higher (or Node.js >= 24.0.0)

More MCP options

Compare MCP servers by category, or browse hosted MCP servers if you prefer an endpoint over a local process.

Maintainer setup documentation.

Recorded tools

Check the linked publisher documentation and your connected client's tool list. Names and availability can vary with the server version and account permissions.

Tool	What it does
clinicaltrials_search_studies	Search studies with full-text and field-specific queries, status/phase/geographic filters, pagination, sorting, and field selection
clinicaltrials_get_study_record	Fetch a single study by NCT ID — full protocol record with optional location/outcome/reference caps
clinicaltrials_get_study_count	Fast total study count for a query, without fetching data
clinicaltrials_get_field_values	Discover valid values for API fields, with per-value study counts
clinicaltrials_get_field_definitions	Resolve valid field names — keyword search, path drill-down, or top-level overview
clinicaltrials_get_study_results	Fetch posted results — outcomes, adverse events, participant flow, baseline — for completed studies
clinicaltrials_find_eligible	Match patient demographics and conditions to eligible recruiting trials

How to install the Clinicaltrialsgov MCP Server

{
  "mcpServers": {
    "clinicaltrialsgov-mcp-server": {
      "type": "streamable-http",
      "url": "https://clinicaltrials.caseyjhand.com/mcp"
    }
  }
}

From the project documentation. Replace placeholders and example paths before connecting.

Configuration

Bun v1.3.0 or higher (or Node.js >= 24.0.0)

Example prompts to try

“Use Clinicaltrialsgov to clinicaltrials search studies.”
“Use Clinicaltrialsgov to clinicaltrials get study results.”
“Use Clinicaltrialsgov to clinicaltrials find eligible.”

Frequently asked questions

Search ClinicalTrials.gov trials, retrieve study details and results, and match patients to eligible trials via MCP. STDIO or Streamable HTTP. Confirm the tools offered by your installed version in the connected client. Tool availability and permissions depend on the server and account configuration.