Civic MCP Server

Most database access work still happens through a UI a human drives. Civic MCP server moves it into the conversation instead. This is a Cloudflare Workers-based Model Context Protocol (MCP) server that provides tools for querying the CIViC (Clinical Interpretation of Variants in Cancer) API. The server converts GraphQL responses into queryable SQLite tables using.

The short version

• GraphQL to SQL Conversion — Automatically converts CIViC API responses into structured SQLite tables
• Efficient Data Storage — Uses Cloudflare Durable Objects with SQLite for data staging and querying
• Smart Response Handling — Optimizes performance by bypassing staging for small responses, errors, and schema introspection queries
• Tool Pipeline —

Getting it running

Setup follows the usual MCP pattern — install or clone the server, register it in your client's configuration file, restart the client.

The tools it exposes

The server publishes 1 tool. What each one is for:

• Prerequisites — The Prerequisites tool exposed by this server

What it needs from you

• A Cloudflare account - Wrangler CLI installed - Claude Desktop app

Things to watch

• It runs with your machine's permissions. That is convenient and also the reason to think about what you point it at before you approve a tool call.
• Keep per-call confirmation enabled while you learn its behaviour; it is the cheapest safeguard you have.

How it compares

Among the database access options, the useful question is rarely "what can it do" but "what does it cost you to run" — permissions, credentials, and how much of your context its toolset consumes. Civic's toolset — Prerequisites — is a fair guide to whether it matches your workflow. It is maintained by QuentinCody; worth a glance at recent repository activity before you build anything load-bearing on it.

This entry was verified against Civic's own documentation before publication; SyncDev keeps the directory reviewed rather than auto-generated.