Bio MCP Bwa MCP Server

MCP (Model Context Protocol) server for the BWA (Burrows-Wheeler Aligner) sequence alignment tool.

Local serverstdioPython

What is the Bio MCP Bwa MCP Server?

MCP (Model Context Protocol) server for the BWA (Burrows-Wheeler Aligner) sequence alignment tool.

What the server does

This MCP server provides access to BWA functionality, allowing AI assistants to perform alignment of short and long sequencing reads to a reference genome.

  • bwa_index — Create an index for a reference genome
  • bwa_mem — Align reads using the BWA-MEM algorithm
  • bwa_aln — Find SA coordinates with the BWA-backtrack algorithm
  • bwa_samse — Generate single-end alignments in SAM format
  • bwa_sampe — Generate paired-end alignments in SAM format
  • Support for large reference genomes and read files

Credentials and setup notes

  • Python 3.9+ - BWA installed (bwa)

More MCP options

Compare MCP servers by category, or browse hosted MCP servers if you prefer an endpoint over a local process.

Maintainer setup documentation.

How to install the Bio MCP Bwa MCP Server

{
  "mcpServers": {
    "bio-bwa": {
      "command": "python",
      "args": [
        "-m",
        "src.server"
      ],
      "cwd": "/path/to/bio-mcp-bwa"
    }
  }
}

From the project documentation. Replace placeholders and example paths before connecting.

Configuration

  • Python 3.9+ - BWA installed (bwa)

Example prompts to try

  • “Use Bio MCP Bwa to Prerequisites.”

Frequently asked questions

MCP (Model Context Protocol) server for the BWA (Burrows-Wheeler Aligner) sequence alignment tool. Confirm the tools offered by your installed version in the connected client. Tool availability and permissions depend on the server and account configuration.