AlphaFold MCP Server

A comprehensive Model Context Protocol server for accessing AlphaFold Protein Structure Database with advanced protein structure prediction tools

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What is the AlphaFold MCP Server?

A comprehensive Model Context Protocol server for accessing AlphaFold Protein Structure Database with advanced protein structure prediction tools

What you get

This MCP server enables seamless integration with AlphaFold's vast collection of protein structure predictions, offering tools for structure retrieval, confidence analysis, batch processing, and visualization preparation. Perfect for researchers, bioinformaticians, and structural biologists working with predicted protein structures.

More MCP options

Compare MCP servers by category, or browse hosted MCP servers if you prefer an endpoint over a local process.

Maintainer setup documentation.

Recorded tools

Check the linked publisher documentation and your connected client's tool list. Names and availability can vary with the server version and account permissions.

ToolWhat it does
get_structure
download_structure
check_availability
search_structures
list_by_organism
get_organism_stats
get_confidence_scores
analyze_confidence_regions
get_prediction_metadata
batch_structure_info
batch_download
batch_confidence_analysis
compare_structures
find_similar_structures
get_coverage_info
validate_structure_quality
export_for_pymol
export_for_chimerax
get_api_status

How to install the AlphaFold MCP Server

{
  "mcpServers": {
    "alphafold-server": {
      "command": "node",
      "args": [
        "/path/to/alphafold-server/build/index.js"
      ]
    }
  }
}

From the project documentation. Replace placeholders and example paths before connecting.

Example prompts to try

  • “Use AlphaFold to Multi.”
  • “Use AlphaFold to Metadata.”
  • “Use AlphaFold to Cross-references.”

Frequently asked questions

A comprehensive Model Context Protocol server for accessing AlphaFold Protein Structure Database with advanced protein structure prediction tools Confirm the tools offered by your installed version in the connected client. Tool availability and permissions depend on the server and account configuration.